FormulaSeek - Similac ProTotal Comfort RTF vs Similac Advance RTF


Updated: 12/7/2024


Introduction

Choosing the right infant formula is a critical decision for parents who choose not to breastfeed, or who supplement breastfeeding with formula. As every baby’s nutritional needs and tolerances are unique, selecting the optimum formula ensures that your baby receives the essential nutrients required for healthy growth and development. Two popular choices among parents are Similac Advance Ready-To-Feed (RTF) and Similac ProTotal Comfort RTF. This blog post will compare these two formulas, helping you make an informed decision for your little one.

Nutritional Composition

Both Similac Advance RTF and Similac ProTotal Comfort RTF are designed to offer complete nutrition but differ in their nutritional components to address different dietary requirements and tolerances.

Similac Advance RTF is modeled after breast milk and features a balanced whey-to-casein protein ratio. It provides carbohydrates primarily from lactose, the natural sugar found in breast milk. Its fat blend includes safflower oil, soy oil, and coconut oil among others, supplying essential fatty acids crucial for growth. This formula includes a complete set of vitamins and minerals including iron and calcium.

Similac ProTotal Comfort RTF uses partially hydrolyzed whey protein, making it easier to digest for babies with sensitivity. The primary carbohydrate is maltodextrin, and the fat blend mirrors that of Similac Advance. This formula is fortified with 2’-FL HMO, a prebiotic that supports the immune system, along with vitamins and minerals.

Key Differences

Key Component Similac Advance RTF Similac ProTotal Comfort RTF
Protein Source Whey-to-Casein ratio Partially Hydrolyzed Whey Protein
Carbohydrate Source Lactose Maltodextrin
Fat Source Safflower Oil, Soy Oil, Coconut Oil Safflower Oil, Soy Oil, Coconut Oil
Prebiotics and Probiotics No 2’-FL HMO (Prebiotic)
Omega-3 (DHA/ARA) Levels Yes Yes
Iron and Calcium Content Yes Yes
Estimated Cost per Ounce $0.50 - $0.60 $0.55 - $0.65
Organic or Non-GMO Non-GMO Non-GMO

Note: Prices are estimated and can vary based on location and retailer.

Special Features and Benefits

Similac Advance RTF contains ingredients that closely mimic the nutritional components found in breast milk, with a focus on providing balanced nutrition for infants. This includes its comprehensive vitamin and mineral profile designed to promote overall health and development.

Similac ProTotal Comfort RTF is specially formulated with partially hydrolyzed protein to cater to babies with sensitive stomachs. It includes 2’-FL HMO, known to foster healthy gut flora and bolster the immune system by promoting the growth of good bacteria similar to those in breastfed infants. This makes it a beneficial choice for infants with digestive issues.

Target Audience

Similac Advance RTF is suited for infants with no particular dietary sensitivities who require a solid foundation of balanced nutrition for growth and development. It is often recommended as a starting point for parents who do not have specific concerns.

Similac ProTotal Comfort RTF targets infants with lactose sensitivity or digestive discomfort. Its partially hydrolyzed protein and prebiotic content make it easier to digest, alleviating potential issues with bloating, gas, or fussiness.

Alternatives to Similac Advance RTF

  • Enfamil NeuroPro Infant Formula
  • Gerber Good Start GentlePro
  • Earth's Best Organic Infant Formula
  • HappyBaby Organic Formula
  • Kendamil Organic Baby Formula

Alternatives to Similac ProTotal Comfort RTF

  • Enfamil Gentlease
  • Gerber Good Start SoothePro
  • Parent's Choice Gentle Formula
  • HappyBaby Sensitive Organic Infant Formula
  • Earth's Best Sensitivity Organic

Potential Drawbacks

While Similac Advance RTF is a comprehensive choice, its lactose content may not be suitable for babies with lactose intolerance. Parents concerned about palm oil might prefer formulas with different fat sources.

Similac ProTotal Comfort RTF, although great for sensitivity, is more expensive and its maltodextrin content can be a concern for parents wishing to avoid this ingredient.

Conclusion

Both Similac Advance RTF and Similac ProTotal Comfort RTF offer unique advantages, catering to different nutritional and digestive needs. Similac Advance is ideal for babies without specific dietary needs, offering a nutritious balance akin to breast milk. Similac ProTotal Comfort, with its gentle, partially hydrolyzed protein, is excellent for babies with sensitive stomachs. Ultimately, parents should consider their baby’s specific needs, consult with a pediatrician, and weigh the cost against benefits when selecting the best formula. Always remember, each child is unique, and what works for one may not work for another.

Sources*

Buy Similac ProTotal Comfort RTF Online

Buy Similac Advance RTF Online

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Nutrient comparison

Similac ProTotal Comfort RTF +/- Data +/- Similac Advance RTF
5.40 g Fat 5.40 g
10.70 g Carbohydrate 0.50 11.20 g
2.32 g 0.25 Protein 2.07 g
1000.00 mg 1000.00 Linoleic Acid 0

Minerals comparison

Items in the left column are unique to that formula, same for the right. Items in the middle are in both.

Similac ProTotal Comfort RTF +/- Minerals +/- Similac Advance RTF
105.00 mg 27.00 Calcium -27.00 78.00 mg
75.00 mg 33.00 Phosphorus -33.00 42.00 mg
6.00 mg 0.00 Magnesium 0.00 6.00 mg
1.80 mg 0.00 Iron 0.00 1.80 mg
0.75 mg 0.00 Zinc 0.00 0.75 mg
5.00 mcg 0.00 Manganese 0.00 5.00 mcg
90.00 mcg 0.00 Copper 0.00 90.00 mcg
15.00 mcg 0.00 Iodine 0.00 15.00 mcg
2.00 mcg 0.00 Selenium 0.00 2.00 mcg
44.00 mg 20.00 Sodium -20.00 24.00 mg
118.00 mg 13.00 Potassium -13.00 105.00 mg
65.00 mg 0.00 Chloride 0.00 65.00 mg

Vitamins comparison

Vitamins from both formulas are listed in the center. If they exist in a formula they will have a value next to them. The difference will be show under the +/- column for easy visibility.

Similac ProTotal Comfort RTF +/- Vitamin +/- Similac Advance RTF
1.50 IU 0.00 Vitamin E 0.00 1.50 IU
8.00 mcg 0.00 Vitamin K 0.00 8.00 mcg
100.00 mcg 0.00 Thiamin (Vit B1) 0.00 100.00 mcg
150.00 mcg 0.00 Riboflavin (Vit B2) 0.00 150.00 mcg
60.00 mcg 0.00 Vitamin B6 0.00 60.00 mcg
0.25 mcg 0.00 Vitamin B12 0.00 0.25 mcg
1050.00 mcg 0.00 Niacin 0.00 1050.00 mcg
15.00 mcg 0.00 Folic Acid 0.00 15.00 mcg
450.00 mcg 0.00 Pantothenic Acid 0.00 450.00 mcg
4.40 mcg 0.00 Biotin 0.00 4.40 mcg
9.00 mg 0.00 Vitamin C 0.00 9.00 mg
24.00 mg 0.00 Choline 0.00 24.00 mg
24.00 mg 0.00 Inositol 0.00 24.00 mg
300.00 IU 0.00 Vitamin A 0.00 300.00 IU
60.00 IU 0.00 Vitamin D 0.00 60.00 IU