FormulaSeek - Similac ProTotal Comfort RTF vs Enfamil Nutramigen RTF


Updated: 12/7/2024


Introduction

Choosing the right infant formula is crucial for a baby’s development, especially when breastfeeding is not an option. It’s vital to select a formula that meets the nutritional needs of the infant while being gentle on their digestive system. Similac ProTotal Comfort RTF and Enfamil Nutramigen RTF are two popular formulas that are often considered by parents. In this blog post, we will explore the nutritional components, key differences, and special features of each to help you make an informed decision.

Nutritional Composition

Both Similac ProTotal Comfort RTF and Enfamil Nutramigen RTF provide essential nutrients to support an infant’s growth and development. Here’s a closer look at their nutritional composition:

Similac ProTotal Comfort is designed for easy digestion and helps reduce fussiness and gas. It typically includes partially hydrolyzed whey protein, corn maltodextrin as a carbohydrate source, and a blend of high oleic safflower oil, soy oil, and coconut oil as fat sources.

Enfamil Nutramigen is a hypoallergenic formula with extensively hydrolyzed casein proteins, crafted particularly for babies with cow’s milk protein allergies. Its carbohydrate source is usually corn syrup solids, and it includes a blend of palm olein oil and modified coconut oil for fats.

Key Differences

Feature Similac ProTotal Comfort RTF Enfamil Nutramigen RTF
Protein Source Partially hydrolyzed whey Extensively hydrolyzed casein
Carbohydrate Source Corn maltodextrin Corn syrup solids
Fat Source High oleic safflower, soy, coconut oils Palm olein, modified coconut oils
Prebiotics and Probiotics 2’-FL HMO (no probiotics) Lactobacillus GG (probiotic)
Omega-3 (DHA/ARA) Levels Yes Yes
Iron and Calcium Content Yes Yes
Estimated Cost per Ounce Approximately $0.18/oz * Approximately $0.21/oz *
Organic or Non-GMO Certification Non-GMO Non-GMO

* Prices are estimated and may vary based on location and retailer.

Special Features and Benefits

Similac ProTotal Comfort is noted for its 2’-FL HMO, an immune-nourishing prebiotic that's similar to those found in breast milk, which supports the child’s developing immune system. It’s specifically intended for gentle tummy comfort, reducing gas and fussiness.

Enfamil Nutramigen, on the other hand, is designed for infants with severe allergies, including cow's milk protein allergy. It comes with Lactobacillus GG, a probiotic that helps support digestive health and manages colic due to cow’s milk allergy.

Target Audience

Similac ProTotal Comfort is suitable for babies who experience digestive discomfort or minor lactose sensitivity. It is especially beneficial for infants showing symptoms such as excess gas or fussiness.

Enfamil Nutramigen is aimed at infants with cow’s milk allergies or colic due to such allergies. Babies with other protein allergies may also benefit from this formula's special hypoallergenic properties.

Alternatives

Alternatives to Similac ProTotal Comfort RTF

  • Similac Sensitive RTF
  • Gerber Good Start Gentle RTF
  • Enfamil Gentlease NeuroPro RTF
  • Earth's Best Organic Dairy Infant Formula
  • Kirkland Signature ProCare Non-GMO Infant Formula

Alternatives to Enfamil Nutramigen RTF

  • Similac Alimentum RTF
  • Gerber Extensive HA
  • Parent's Choice Hypoallergenic RTF
  • Neocate Infant DHA/ARA
  • EleCare Infant Formula

Potential Drawbacks

Similac ProTotal Comfort can be on the pricier side for some families, and availability may be limited depending on your area. Moreover, it might not be suitable for infants with severe protein allergies.

Enfamil Nutramigen is typically costlier than regular formulas and may be less accessible in stores. Some parents also report concerns about its taste, which may lead to fussiness during feeding.

Conclusion

In summary, both Similac ProTotal Comfort RTF and Enfamil Nutramigen RTF serve unique needs and cater to different sets of infants. Similac is ideal for mild tummy issues and overall comfort, while Enfamil provides essential nutrition for infants with severe allergies. It is advised that parents consult with their pediatrician before making any changes to their baby’s diet, ensuring the selected formula meets all health needs and dietary requirements.

Sources*

Buy Similac ProTotal Comfort RTF Online

Buy Enfamil Nutramigen RTF Online

+ Links are reviewed periodically for accuracy; failing links might mean the product is currently unavailable.

View All Compares

Start here

Nutrient comparison

Similac ProTotal Comfort RTF +/- Data +/- Enfamil Nutramigen RTF
5.40 g 0.10 Fat 5.30 g
10.70 g 0.40 Carbohydrate 10.30 g
2.32 g Protein 0.48 2.80 g
1000.00 mg 140.00 Linoleic Acid 860.00 mg

Minerals comparison

Items in the left column are unique to that formula, same for the right. Items in the middle are in both.

Similac ProTotal Comfort RTF +/- Minerals +/- Enfamil Nutramigen RTF
105.00 mg 11.00 Calcium -11.00 94.00 mg
75.00 mg 23.00 Phosphorus -23.00 52.00 mg
6.00 mg -2.00 Magnesium 2.00 8.00 mg
1.80 mg 0.00 Iron 0.00 1.80 mg
0.75 mg -0.25 Zinc 0.25 1.00 mg
5.00 mcg -20.00 Manganese 20.00 25.00 mcg
90.00 mcg 15.00 Copper -15.00 75.00 mcg
15.00 mcg 0.00 Iodine 0.00 15.00 mcg
2.00 mcg -0.80 Selenium 0.80 2.80 mcg
44.00 mg -3.00 Sodium 3.00 47.00 mg
118.00 mg 8.00 Potassium -8.00 110.00 mg
65.00 mg -21.00 Chloride 21.00 86.00 mg

Vitamins comparison

Vitamins from both formulas are listed in the center. If they exist in a formula they will have a value next to them. The difference will be show under the +/- column for easy visibility.

Similac ProTotal Comfort RTF +/- Vitamin +/- Enfamil Nutramigen RTF
1.50 IU -0.50 Vitamin E 0.50 2.00 IU
8.00 mcg -1.00 Vitamin K 1.00 9.00 mcg
100.00 mcg 20.00 Thiamin (Vit B1) -20.00 80.00 mcg
150.00 mcg 60.00 Riboflavin (Vit B2) -60.00 90.00 mcg
60.00 mcg 0.00 Vitamin B6 0.00 60.00 mcg
0.25 mcg -0.05 Vitamin B12 0.05 0.30 mcg
1050.00 mcg 50.00 Niacin -50.00 1000.00 mcg
15.00 mcg -1.00 Folic Acid 1.00 16.00 mcg
450.00 mcg -50.00 Pantothenic Acid 50.00 500.00 mcg
4.40 mcg 1.40 Biotin -1.40 3.00 mcg
9.00 mg -3.00 Vitamin C 3.00 12.00 mg
24.00 mg 0.00 Choline 0.00 24.00 mg
24.00 mg 7.00 Inositol -7.00 17.00 mg
300.00 IU 0.00 Vitamin A 0.00 300.00 IU
60.00 IU 10.00 Vitamin D -10.00 50.00 IU