FormulaSeek - Similac ProTotal Comfort vs Enfamil NeuroPro Gentlease RTF


Updated: 12/7/2024


Introduction

Choosing the right infant formula is one of the critical decisions new parents must make in ensuring their baby's nutritional well-being. With numerous options available on the market, identifying a formula that meets the dietary needs and sensitivities of your child is imperative. Two popular options are Similac ProTotal Comfort and Enfamil NeuroPro Gentlease RTF. Each formula has distinct characteristics tailored to specific infant needs, but how do they compare? Let's dive in and explore these two options.

Nutritional Composition

The nutritional components in infant formulas play a significant role in their effectiveness and suitability for individual babies.

Similac ProTotal Comfort features partially hydrolyzed protein, primarily whey, which is easier to digest for infants. It incorporates lactose as its primary carbohydrate source, supporting a balanced energy supply. The fat blend includes high oleic safflower oil, soy oil, and coconut oil.

Enfamil NeuroPro Gentlease RTF aims to reduce fussiness, gas, and crying, thanks to a partially hydrolyzed nonfat milk and whey protein concentrate solids as the protein source. Its carbohydrate component is primarily corn syrup solids, designed for easier digestion. The formula uses a mix of vegetable oils including high oleic sunflower oil, coconut oil, and palm olein oil.

Key Differences

Feature Similac ProTotal Comfort Enfamil NeuroPro Gentlease RTF
Protein Source Partially hydrolyzed whey Partially hydrolyzed nonfat milk and whey protein concentrate
Carbohydrate Source Lactose Corn syrup solids
Fat Source Safflower oil, soy oil, coconut oil Sunflower oil, coconut oil, palm olein oil
Prebiotics and Probiotics 2'-FL HMO prebiotic Lacking additional prebiotics/probiotics
Omega-3 (DHA/ARA) Present Present
Iron and Calcium Content Iron: 1.89mg; Calcium: 105mg (per 100 calories) Iron: 1.8mg; Calcium: 118mg (per 100 calories)
Estimated Cost per Ounce $0.50 $0.70
Organic or Non-GMO Certification Non-GMO Non-GMO

*Prices are estimated and may vary by location and retailer.

Special Features and Benefits

Similac ProTotal Comfort boasts the inclusion of 2'-FL HMO prebiotic, which mirrors a prebiotic found in breast milk. This helps support the immune system and digestive health.

Enfamil NeuroPro Gentlease RTF includes MFGM (Milk Fat Globule Membrane) and DHA, which are designed to support cognitive development, making it a noteworthy option for brain-building nutrition.

Target Audience

Similac ProTotal Comfort is well-suited for infants who have lactose sensitivity but do not require a completely lactose-free formula. Its gentle, partially hydrolyzed proteins and prebiotics help address digestive sensitivities.

Enfamil NeuroPro Gentlease RTF, on the other hand, is aimed at babies who experience fussiness and gas due to protein sensitivities. It offers a hearty blend for cognitive advancement while soothing digestive discomfort.

Alternatives

Similac ProTotal Comfort Alternatives

  1. Gerber Good Start GentlePro
  2. Earth's Best Organic Sensitivity
  3. Happy Baby Organic Infant Formula
  4. Plum Organics Gentle
  5. Parent's Choice Gentle

Enfamil NeuroPro Gentlease RTF Alternatives

  1. Similac Sensitive
  2. Gerber Good Start Soothe
  3. Parent's Choice Tender
  4. Up & Up Advantage
  5. Earth's Best Gentle Formula

Potential Drawbacks

For Similac ProTotal Comfort, some parents might be concerned about the presence of soy oil and the higher price point. Availability in some regions may also be limited.

Enfamil NeuroPro Gentlease RTF may be less appealing to parents wary of using formulas with corn syrup solids as a carbohydrate source. Additionally, the cost per ounce is relatively higher compared to powdered alternatives.

Conclusion

Both Similac ProTotal Comfort and Enfamil NeuroPro Gentlease RTF offer beneficial blends targeted to soothe digestive issues and bolster development in infants. Similac stands out for its incorporation of prebiotics, whereas Enfamil shines with its emphasis on cognitive-enhancing nutrients. Ultimately, the choice between these two depends on the specific dietary requirements and sensitivities of your infant.

Regardless of your choice, it's essential to consult with a pediatrician to ensure the selected formula aligns with your baby's health needs and supports their growth trajectory.

Sources*

Buy Similac ProTotal Comfort Online

Buy Enfamil NeuroPro Gentlease RTF Online

+ Links are reviewed periodically for accuracy; failing links might mean the product is currently unavailable.

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Nutrient comparison

Similac ProTotal Comfort +/- Data +/- Enfamil NeuroPro Gentlease RTF
5.40 g 0.10 Fat 5.30 g
10.70 g Carbohydrate 0.10 10.80 g
2.32 g 0.02 Protein 2.30 g
1000.00 mg 220.00 Linoleic Acid 780.00 mg

Minerals comparison

Items in the left column are unique to that formula, same for the right. Items in the middle are in both.

Similac ProTotal Comfort +/- Minerals +/- Enfamil NeuroPro Gentlease RTF
105.00 mg 23.00 Calcium -23.00 82.00 mg
75.00 mg 29.00 Phosphorus -29.00 46.00 mg
6.00 mg -2.00 Magnesium 2.00 8.00 mg
1.80 mg 0.00 Iron 0.00 1.80 mg
0.75 mg -0.25 Zinc 0.25 1.00 mg
5.00 mcg -10.00 Manganese 10.00 15.00 mcg
90.00 mcg 15.00 Copper -15.00 75.00 mcg
15.00 mcg 0.00 Iodine 0.00 15.00 mcg
2.00 mcg -0.80 Selenium 0.80 2.80 mcg
44.00 mg 4.00 Sodium -4.00 40.00 mg
118.00 mg 10.00 Potassium -10.00 108.00 mg
65.00 mg 2.00 Chloride -2.00 63.00 mg

Vitamins comparison

Vitamins from both formulas are listed in the center. If they exist in a formula they will have a value next to them. The difference will be show under the +/- column for easy visibility.

Similac ProTotal Comfort +/- Vitamin +/- Enfamil NeuroPro Gentlease RTF
1.50 IU -0.50 Vitamin E 0.50 2.00 IU
8.00 mcg -1.00 Vitamin K 1.00 9.00 mcg
100.00 mcg 20.00 Thiamin (Vit B1) -20.00 80.00 mcg
150.00 mcg 10.00 Riboflavin (Vit B2) -10.00 140.00 mcg
60.00 mcg 0.00 Vitamin B6 0.00 60.00 mcg
0.25 mcg -0.05 Vitamin B12 0.05 0.30 mcg
1050.00 mcg 50.00 Niacin -50.00 1000.00 mcg
15.00 mcg -1.00 Folic Acid 1.00 16.00 mcg
450.00 mcg -50.00 Pantothenic Acid 50.00 500.00 mcg
4.40 mcg 1.40 Biotin -1.40 3.00 mcg
9.00 mg -3.00 Vitamin C 3.00 12.00 mg
24.00 mg 0.00 Choline 0.00 24.00 mg
24.00 mg 0.00 Inositol 0.00 24.00 mg
300.00 IU 0.00 Vitamin A 0.00 300.00 IU
60.00 IU 0.00 Vitamin D 0.00 60.00 IU