FormulaSeek - Similac ProTotal Comfort vs Enfamil NeuroPro Gentlease


Updated: 12/7/2024


Introduction

Choosing the right infant formula can be a crucial decision for new parents, particularly when breastfeeding may not be feasible or desired. The right formula ensures that your baby receives the necessary nutrients to support healthy growth and development. Two popular choices among parents are Similac ProTotal Comfort and Enfamil NeuroPro Gentlease. Both of these formulas are designed for babies who may have sensitive stomachs and have distinct features that make them stand out in the infant formula market.

Nutritional Composition

Understanding what goes into each formula is essential in choosing the right one for your baby. Both Similac ProTotal Comfort and Enfamil NeuroPro Gentlease offer comprehensive nutritional profiles, but they formulate these components differently.

Similac ProTotal Comfort uses a protein that is partially hydrolyzed, which is easier for some babies to digest. The primary carbohydrate source is maltodextrin, and it uses a blend of high oleic safflower oil, soy, and coconut oils for its fat content. It also includes a unique blend of prebiotics, vitamins, and minerals, including iron and calcium, to meet infant dietary requirements.

Enfamil NeuroPro Gentlease also contains partially hydrolyzed proteins made from partially broken down whey to ease digestion. Its carbohydrate component is mainly lactose with some corn syrup solids. Moreover, its fat composition includes a mix of palm olein oil, soy, coconut, and high oleic sunflower oils. Enfamil uses a dual prebiotic blend to support digestive health and includes essential vitamins and minerals, including iron and calcium.

Key Differences

Feature Similac ProTotal Comfort Enfamil NeuroPro Gentlease
Protein Source Partially hydrolyzed whey protein Partially hydrolyzed whey protein
Carbohydrate Source Maltodextrin Lactose, corn syrup solids
Fat Source Safflower, soy, coconut oils Palm olein, soy, coconut, sunflower oils
Prebiotics and Probiotics Prebiotics (2’-FL HMO) Dual prebiotics
Omega-3 (DHA/ARA) Levels Included Included
Iron and Calcium Content Included Included
Estimated Cost per Ounce Approx. $0.40 per ounce Approx. $0.35 per ounce
Organic or Non-GMO Certification Non-GMO Non-GMO

Special Features and Benefits

Similac ProTotal Comfort: This formula is specially designed for babies with lactose sensitivity due to its use of 100% lactose-free carbohydrate sources. The addition of 2’FL HMO prebiotics supports gut health and immune function.

Enfamil NeuroPro Gentlease: Known for its brain-building DHA, this formula supports cognitive development. It also has a reputation for reducing fussiness, gas, and crying in as little as 24 hours due to its partially hydrolyzed proteins and gentle formula.

Target Audience

Similac ProTotal Comfort is often recommended for babies with lactose sensitivity or who exhibit digestive discomfort related to lactose. Conversely, Enfamil NeuroPro Gentlease is targeted toward infants who experience heightened fussiness or gas and babies whose families seek enhanced nutrient support for brain development.

Alternatives

Alternatives to Similac ProTotal Comfort:

  • Gerber Good Start SoothePro
  • Earth’s Best Organic Sensitivity
  • Baby’s Only Organic Gentle Dairy
  • Parent’s Choice Gentle Formula
  • Up & Up Complete Comfort
  • Nutramigen with Enflora LGG

Alternatives to Enfamil NeuroPro Gentlease:

  • Similac Pro-Sensitive
  • Happy Baby Organic Infant Formula
  • Earth's Best Organic Gentle
  • Gerber Good Start GentlePro
  • Parent’s Choice Advantage HMO
  • Store-brand (Kroger, CVS) Gentle

Potential Drawbacks

Similac ProTotal Comfort: Some parents note that this formula may be a bit higher in cost compared to others. Additionally, availability might be an issue due to its specific formulation catering to sensitive digestive needs.

Enfamil NeuroPro Gentlease: While generally cost-effective, some parents report occasional stock issues. The inclusion of corn syrup solids may be a concern for those trying to avoid this component in their baby's diet.

Conclusion

Both Similac ProTotal Comfort and Enfamil NeuroPro Gentlease offer unique advantages for infants with specific dietary needs or sensitivities. Similac ProTotal Comfort is a solid choice for those seeking a lactose-free option, while Enfamil NeuroPro Gentlease is excellent for reducing gas and fussiness with the added benefit of DHA for brain development. Ultimately, the choice between these two will depend on your baby’s unique needs, family preferences, and pediatrician recommendations. Always consult with a healthcare professional when deciding on infant formula to ensure your baby receives tailored nutritional support.

Sources*

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Buy Enfamil NeuroPro Gentlease Online

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Nutrient comparison

Similac ProTotal Comfort +/- Data +/- Enfamil NeuroPro Gentlease
5.40 g 0.10 Fat 5.30 g
10.70 g Carbohydrate 0.10 10.80 g
2.32 g 0.02 Protein 2.30 g
1000.00 mg 220.00 Linoleic Acid 780.00 mg

Minerals comparison

Items in the left column are unique to that formula, same for the right. Items in the middle are in both.

Similac ProTotal Comfort +/- Minerals +/- Enfamil NeuroPro Gentlease
105.00 mg 23.00 Calcium -23.00 82.00 mg
75.00 mg 29.00 Phosphorus -29.00 46.00 mg
6.00 mg -2.00 Magnesium 2.00 8.00 mg
1.80 mg 0.00 Iron 0.00 1.80 mg
0.75 mg -0.25 Zinc 0.25 1.00 mg
5.00 mcg -10.00 Manganese 10.00 15.00 mcg
90.00 mcg 15.00 Copper -15.00 75.00 mcg
15.00 mcg 0.00 Iodine 0.00 15.00 mcg
2.00 mcg -0.80 Selenium 0.80 2.80 mg
44.00 mg 4.00 Sodium -4.00 40.00 mg
118.00 mg 10.00 Potassium -10.00 108.00 mg
65.00 mg 2.00 Chloride -2.00 63.00 mg

Vitamins comparison

Vitamins from both formulas are listed in the center. If they exist in a formula they will have a value next to them. The difference will be show under the +/- column for easy visibility.

Similac ProTotal Comfort +/- Vitamin +/- Enfamil NeuroPro Gentlease
1.50 IU -0.50 Vitamin E 0.50 2.00 IU
8.00 mcg -1.00 Vitamin K 1.00 9.00 mcg
100.00 mcg 20.00 Thiamin (Vit B1) -20.00 80.00 mcg
150.00 mcg 10.00 Riboflavin (Vit B2) -10.00 140.00 mcg
60.00 mcg 54.00 Vitamin B6 -54.00 6.00 mcg
0.25 mcg -0.05 Vitamin B12 0.05 0.30 mcg
1050.00 mcg 50.00 Niacin -50.00 1000.00 mcg
15.00 mcg -1.00 Folic Acid 1.00 16.00 mcg
450.00 mcg -50.00 Pantothenic Acid 50.00 500.00 mcg
4.40 mcg 1.40 Biotin -1.40 3.00 mcg
9.00 mg -3.00 Vitamin C 3.00 12.00 mg
24.00 mg 0.00 Choline 0.00 24.00 mg
24.00 mg 0.00 Inositol 0.00 24.00 mg
300.00 IU 0.00 Vitamin A 0.00 300.00 IU
60.00 IU 0.00 Vitamin D 0.00 60.00 IU