FormulaSeek - Similac ProTotal Comfort vs Enfamil NeuroPro


Updated: 12/7/2024


Introduction

Choosing the right infant formula is a critical decision for parents who are unable to breastfeed or who choose to supplement breastfeeding. With numerous options available, the decision can often be overwhelming. Two popular choices amongst parents today are Enfamil NeuroPro and Similac ProTotal Comfort. Each of these formulas offers unique benefits designed to support your baby’s growth and development. This blog post will compare these two infant formulas, helping you make an informed decision for your little one.

Nutritional Composition

The nutritional composition of infant formula is essential to evaluate, as it directly affects your baby's health and development. Enfamil NeuroPro and Similac ProTotal Comfort are both designed to provide balanced nutrition but accomplish this in different ways:

  • Enfamil NeuroPro: This formula is enriched with MFGM and Omega-3 DHA, aiming to support brain development. It includes proteins derived mainly from whey and casein.
  • Similac ProTotal Comfort: This formula is designed for sensitive tummies, offering partially hydrolyzed protein and is rich in DHA and prebiotics to promote digestive health.

Key Differences

Criteria Enfamil NeuroPro Similac ProTotal Comfort
Protein Source 20% whey, 80% casein Partially hydrolyzed protein
Carbohydrate Source Lactose Maltodextrin
Fat Source Palm olein, soy, coconut, high oleic sunflower oil Safflower, soy, coconut oil
Prebiotics and Probiotics Mannose and Galactooligosaccharides (GOS) 2’-FL HMO prebiotics
Omega-3 (DHA/ARA) Levels 0.32% of total fatty acids 0.15% DHA
Iron and Calcium Content 1.8 mg iron, 78 mg calcium per 100 kcal 1.93 mg iron, 78 mg calcium per 100 kcal
Estimated Cost Per Ounce Approximately $0.24 per ounce Approximately $0.28 per ounce
Organic or Non-GMO Certification Non-GMO Non-GMO

Special Features and Benefits

Enfamil NeuroPro: One distinguishing feature of Enfamil NeuroPro is the inclusion of MFGM, a fat-protein blend that’s believed to support cognitive development similar to the benefits of breast milk. The formula also delivers a high level of DHA to support brain and eye development.

Similac ProTotal Comfort: This formula's partially hydrolyzed protein makes it particularly beneficial for babies with sensitive stomachs. The inclusion of 2’-FL HMO, identical to that found in breast milk, is a prebiotic that strengthens the infant’s immune system.

Target Audience

Enfamil NeuroPro: This formula is ideal for parents looking to support their baby's brain development without specific digestive concerns. It suits babies without protein sensitivity and who digest combined whey and casein proteins well.

Similac ProTotal Comfort: Best for infants with sensitive stomachs or parents who notice gassiness or fussiness in their babies. The partially hydrolyzed protein is gentler on the stomach, which may be beneficial for lactose-sensitive babies.

Alternatives

Enfamil NeuroPro Alternatives

  • Gerber Good Start GentlePro
  • Enfamil Enspire Infant Formula
  • Earth’s Best Organic Infant Formula
  • Happy Baby Organic
  • Plum Organics Gentle Infant Formula

Similac ProTotal Comfort Alternatives

  • Similac Sensitive
  • Similac Alimentum
  • Gerber Extensive HA
  • Enfamil Nutramigen
  • Earth’s Best Sensitivity

Potential Drawbacks

Enfamil NeuroPro: Some parents might find the inclusion of palm olein oil controversial due to potential impacts on calcium retention. Additionally, its slightly higher cost could be a consideration.

Similac ProTotal Comfort: While designed for sensitive stomachs, some babies might not respond well to the maltodextrin as a carbohydrate source. Cost and availability could also be concerns for some households.

Conclusion

In summary, both Enfamil NeuroPro and Similac ProTotal Comfort offer unique benefits catering to different infant needs. Enfamil NeuroPro is better suited for brain development support and general use, whereas Similac ProTotal Comfort is beneficial for babies with sensitive digestive systems. Parents are encouraged to consult with their pediatrician to determine which formula is most appropriate for their baby’s specific health needs and nutritional requirements.

Note: Prices are estimated and may vary based on location and retailer.

Sources*

Buy Similac ProTotal Comfort Online

Buy Enfamil NeuroPro Online

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Nutrient comparison

Similac ProTotal Comfort +/- Data +/- Enfamil NeuroPro
5.40 g 0.10 Fat 5.30 g
10.70 g Carbohydrate 0.60 11.30 g
2.32 g 0.22 Protein 2.10 g
1000.00 mg 220.00 Linoleic Acid 780.00 mg

Minerals comparison

Items in the left column are unique to that formula, same for the right. Items in the middle are in both.

Similac ProTotal Comfort +/- Minerals +/- Enfamil NeuroPro
105.00 mg 27.00 Calcium -27.00 78.00 mg
75.00 mg 32.00 Phosphorus -32.00 43.00 mg
6.00 mg -2.00 Magnesium 2.00 8.00 mg
1.80 mg 0.00 Iron 0.00 1.80 mg
0.75 mg -0.25 Zinc 0.25 1.00 mg
5.00 mcg -10.00 Manganese 10.00 15.00 mcg
90.00 mcg 15.00 Copper -15.00 75.00 mcg
15.00 mcg 0.00 Iodine 0.00 15.00 mcg
2.00 mcg -0.80 Selenium 0.80 2.80 mcg
44.00 mg 17.00 Sodium -17.00 27.00 mg
118.00 mg 10.00 Potassium -10.00 108.00 mg
65.00 mg 2.00 Chloride -2.00 63.00 mg

Vitamins comparison

Vitamins from both formulas are listed in the center. If they exist in a formula they will have a value next to them. The difference will be show under the +/- column for easy visibility.

Similac ProTotal Comfort +/- Vitamin +/- Enfamil NeuroPro
60.00 IU Vitamin D
1.50 IU -0.50 Vitamin E 0.50 2.00 IU
8.00 mcg -1.00 Vitamin K 1.00 9.00 mcg
100.00 mcg 20.00 Thiamin (Vit B1) -20.00 80.00 mcg
150.00 mcg 10.00 Riboflavin (Vit B2) -10.00 140.00 mcg
60.00 mcg 0.00 Vitamin B6 0.00 60.00 mcg
0.25 mcg -0.05 Vitamin B12 0.05 0.30 mcg
1050.00 mcg 50.00 Niacin -50.00 1000.00 mcg
15.00 mcg -1.00 Folic Acid 1.00 16.00 mcg
450.00 mcg -50.00 Pantothenic Acid 50.00 500.00 mcg
4.40 mcg 1.40 Biotin -1.40 3.00 mcg
9.00 mg -61.00 Vitamin C 61.00 70.00 IU
24.00 mg 0.00 Choline 0.00 24.00 mg
24.00 mg 0.00 Inositol 0.00 24.00 mg
300.00 IU 0.00 Vitamin A 0.00 300.00 IU