FormulaSeek - Similac Advance RTF vs Enfamil Nutramigen


Updated: 12/7/2024


Introduction

Choosing the right infant formula is critical for the nutritional well-being of your baby, especially when breastfeeding is not an option. With a myriad of choices available, selecting the right formula can be daunting. Today, we explore two popular infant formulas: Similac Advance Ready-to-Feed (RTF) and Enfamil Nutramigen. This comparison will help you make an informed decision that best suits your baby's needs.

Nutritional Composition

The nutritional composition of infant formulas significantly affects a baby's growth and development. Similac Advance RTF is known for its closeness to breast milk and includes DHA, ARA, and various vitamins and minerals. It relies on cow’s milk protein with a balanced whey-to-casein ratio, lactose as its carbohydrate source, and includes safflower oil among its fat sources. Enfamil Nutramigen stands out for its hypoallergenic properties by using extensively hydrolyzed casein protein, corn syrup solids as its carbohydrate source, and a blend of oils for fats.

Key Differences

Feature Similac Advance RTF Enfamil Nutramigen
Protein Source Cow's milk, Whey, Casein Extensively hydrolyzed Casein
Carbohydrate Source Lactose Corn syrup solids
Fat Source Safflower oil, Soy oil Oleic safflower oil, Soy oil
Prebiotics and Probiotics Prebiotics included Probiotics included
Omega-3 (DHA/ARA) Included Included
Iron and Calcium Standard levels Standard levels
Estimated Cost Per Ounce ~$0.30 ~$0.50
Organic or Non-GMO Certification Non-GMO Non-GMO

Special Features and Benefits

Similac Advance RTF is designed to provide complete nutrition that mimics breast milk, with added prebiotics to support digestive health. Enfamil Nutramigen is formulated to reduce colic related to cow's milk protein allergy within 48 hours. Its hydrolyzed proteins and the presence of probiotics aid in developing a balanced gut microbiome.

Target Audience

Similac Advance RTF is ideal for healthy newborns and infants without specific dietary restrictions or allergies. Enfamil Nutramigen is particularly beneficial for babies with allergies or sensitivity to cow's milk protein, lactose intolerance, or colic.

Alternatives to Similac Advance RTF

  • Gerber Good Start Gentle
  • Earth's Best Organic Dairy Infant Formula
  • Happy Baby Organic Infant Formula
  • Kirkland Signature ProCare
  • Parent's Choice Advantage Formula

Alternatives to Enfamil Nutramigen

  • Similac Alimentum
  • Gerber Extensive HA
  • EleCare Infant Formula
  • Neocate Infant DHA/ARA
  • Enfamil PurAmino

Potential Drawbacks

Similac Advance RTF may not be suitable for infants with lactose intolerance or cow's milk protein allergy. Additionally, some parents may find the cost to be higher compared to powder formulas. Enfamil Nutramigen, while excellent for allergic reactions, is more expensive per ounce and may not be easily accessible in all regions.

Conclusion

Both Similac Advance RTF and Enfamil Nutramigen have their unique advantages, making them suitable for different infant needs. Similac Advance RTF is a great choice for parents seeking a nutrient-complete formula resembling breast milk. On the other hand, Enfamil Nutramigen is advisable for infants with milk allergies or colic symptoms. As always, consult your pediatrician before settling on an infant formula to ensure the best nutrition for your baby.

Sources*

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Nutrient comparison

Similac Advance RTF +/- Data +/- Enfamil Nutramigen
5.40 g 0.10 Fat 5.30 g
11.20 g 0.90 Carbohydrate 10.30 g
2.07 g Protein 0.73 2.80 g
0 Linoleic Acid 780.00 780.00 mg

Minerals comparison

Items in the left column are unique to that formula, same for the right. Items in the middle are in both.

Similac Advance RTF +/- Minerals +/- Enfamil Nutramigen
78.00 mg -16.00 Calcium 16.00 94.00 mg
42.00 mg -10.00 Phosphorus 10.00 52.00 mg
6.00 mg -2.00 Magnesium 2.00 8.00 mg
1.80 mg 0.00 Iron 0.00 1.80 mg
0.75 mg -0.25 Zinc 0.25 1.00 mg
5.00 mcg -20.00 Manganese 20.00 25.00 mcg
90.00 mcg 15.00 Copper -15.00 75.00 mcg
15.00 mcg 0.00 Iodine 0.00 15.00 mcg
2.00 mcg -0.80 Selenium 0.80 2.80 mcg
24.00 mg -23.00 Sodium 23.00 47.00 mg
105.00 mg -5.00 Potassium 5.00 110.00 mg
65.00 mg -21.00 Chloride 21.00 86.00 mg

Vitamins comparison

Vitamins from both formulas are listed in the center. If they exist in a formula they will have a value next to them. The difference will be show under the +/- column for easy visibility.

Similac Advance RTF +/- Vitamin +/- Enfamil Nutramigen
24.00 mg Inositol
300.00 IU 0.00 Vitamin A 0.00 300.00 IU
60.00 IU 0.00 Vitamin D 0.00 60.00 IU
1.50 IU -0.50 Vitamin E 0.50 2.00 IU
8.00 mcg -1.00 Vitamin K 1.00 9.00 mcg
100.00 mcg 20.00 Thiamin (Vit B1) -20.00 80.00 mcg
150.00 mcg 60.00 Riboflavin (Vit B2) -60.00 90.00 mcg
60.00 mcg 0.00 Vitamin B6 0.00 60.00 mcg
0.25 mcg -0.05 Vitamin B12 0.05 0.30 mcg
1050.00 mcg 50.00 Niacin -50.00 1000.00 mcg
15.00 mcg -1.00 Folic Acid 1.00 16.00 mcg
450.00 mcg -50.00 Pantothenic Acid 50.00 500.00 mcg
4.40 mcg 1.40 Biotin -1.40 3.00 mg
9.00 mg -3.00 Vitamin C 3.00 12.00 mg
24.00 mg 0.00 Choline 0.00 24.00 mg