FormulaSeek - Enfamil Nutramigen vs Similac ProTotal Comfort


Updated: 12/7/2024


Introduction

Choosing the right infant formula is crucial for the healthy growth and development of your baby, especially when breastfeeding is not an option. Among the myriad options available, two well-regarded formulas stand out: Similac ProTotal Comfort and Enfamil Nutramigen. These formulas are designed to meet specific needs, offering tailored nutrition for different digestive and dietary sensitivities. In this blog, we will delve into the differences and benefits of these two brands to help guide your choice.

Nutritional Composition

Similac ProTotal Comfort is formulated with partially hydrolyzed protein for easier digestion. It uses whey protein and includes 2'-FL HMO prebiotic, which mimics some of the immune benefits of breast milk. The carbohydrate source primarily consists of corn maltodextrin, and it incorporates a fat blend devoid of palm olein oil to promote calcium absorption.

Enfamil Nutramigen, on the other hand, offers extensively hydrolyzed casein protein for babies with severe allergies or lactose intolerance. It uses corn syrup solids as a carbohydrate source. The formula includes a fat blend with MCT oils that aid digestion, and it is enriched with DHA and ARA for brain and eye development.

Key Differences

Feature Similac ProTotal Comfort Enfamil Nutramigen
Protein Source Partially Hydrolyzed Whey Extensively Hydrolyzed Casein
Carbohydrate Source Corn Maltodextrin Corn Syrup Solids
Fat Source No Palm Olein Oil With MCT Oils
Prebiotics and Probiotics 2'-FL HMO Prebiotic Lactobacillus GG Probiotic
Omega-3 DHA Levels Included Included
Iron and Calcium Content Included Included
Estimated Cost per Ounce ~$0.25 ~$0.50
Organic or non-GMO Certification Non-GMO Non-GMO

Special Features and Benefits

Similac ProTotal Comfort provides partially hydrolyzed protein, making it suitable for sensitive tummies. Its inclusion of 2'-FL HMO prebiotic aids in nurturing your baby’s developing immune system. Without palm olein oil, it also promotes better calcium absorption for stronger bones.

Enfamil Nutramigen is crafted for babies with severe allergies such as milk protein allergy. The extensively hydrolyzed protein makes it easier to digest and helps alleviate allergic reactions. Additionally, its MCT oil content simplifies fat digestion, beneficial for infants with specific gastrointestinal conditions. It also includes probiotics to further support digestive health.

Target Audience

Similac ProTotal Comfort is best for infants who experience fussiness and gas due to lactose sensitivity or need a gentler formula to soothe their digestive system.

Enfamil Nutramigen is ideal for babies with milk protein allergies or severe food allergies, especially those who have displayed a sensitivity to lactose.

Alternatives

Alternatives to Similac ProTotal Comfort

  • Gerber Good Start GentlePro
  • Enfamil Gentlease
  • Earth’s Best Organic Sensitivity
  • Happy Baby Organics Sensitive
  • Parent’s Choice Tender

Alternatives to Enfamil Nutramigen

  • Similac Alimentum
  • Gerber Extensive HA
  • EleCare Hypoallergenic Infant Formula
  • PurAmino Hypoallergenic
  • Neocate Infant DHA/ARA

Potential Drawbacks

Similac ProTotal Comfort can be slightly more affordable, but some parents may find it lacks the specialized proteins required for severe allergy cases. Additionally, individual tolerance varies, and not every baby may respond favorably to its composition.

Enfamil Nutramigen is quite effective for babies with allergies, but its cost is significantly higher. Also, some parents point out taste differences that may lead to acceptance issues by some infants.

Conclusion

Both Similac ProTotal Comfort and Enfamil Nutramigen cater to specific needs and offer unique benefits for different infant dietary challenges. Similac ProTotal Comfort is excellent for babies with mild sensitivities, offering additional immune support through prebiotics. Enfamil Nutramigen, with its extensive hydrolysis of proteins, is suited for infants with severe allergies. As always, it is paramount to consult with a pediatrician to determine the best formula for your baby's specific needs and health conditions.

Note: Prices mentioned are estimated and may vary depending on retailer and location.

Sources*

Buy Enfamil Nutramigen Online

Buy Similac ProTotal Comfort Online

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Nutrient comparison

Enfamil Nutramigen +/- Data +/- Similac ProTotal Comfort
5.30 g Fat 0.10 5.40 g
10.30 g Carbohydrate 0.40 10.70 g
2.80 g 0.48 Protein 2.32 g
780.00 mg Linoleic Acid 220.00 1000.00 mg

Minerals comparison

Items in the left column are unique to that formula, same for the right. Items in the middle are in both.

Enfamil Nutramigen +/- Minerals +/- Similac ProTotal Comfort
94.00 mg -11.00 Calcium 11.00 105.00 mg
52.00 mg -23.00 Phosphorus 23.00 75.00 mg
8.00 mg 2.00 Magnesium -2.00 6.00 mg
1.80 mg 0.00 Iron 0.00 1.80 mg
1.00 mg 0.25 Zinc -0.25 0.75 mg
25.00 mcg 20.00 Manganese -20.00 5.00 mcg
75.00 mcg -15.00 Copper 15.00 90.00 mcg
15.00 mcg 0.00 Iodine 0.00 15.00 mcg
2.80 mcg 0.80 Selenium -0.80 2.00 mcg
47.00 mg 3.00 Sodium -3.00 44.00 mg
110.00 mg -8.00 Potassium 8.00 118.00 mg
86.00 mg 21.00 Chloride -21.00 65.00 mg

Vitamins comparison

Vitamins from both formulas are listed in the center. If they exist in a formula they will have a value next to them. The difference will be show under the +/- column for easy visibility.

Enfamil Nutramigen +/- Vitamin +/- Similac ProTotal Comfort
300.00 IU 0.00 Vitamin A 0.00 300.00 IU
60.00 IU 0.00 Vitamin D 0.00 60.00 IU
2.00 IU 0.50 Vitamin E -0.50 1.50 IU
9.00 mcg 1.00 Vitamin K -1.00 8.00 mcg
80.00 mcg -20.00 Thiamin (Vit B1) 20.00 100.00 mcg
90.00 mcg -60.00 Riboflavin (Vit B2) 60.00 150.00 mcg
60.00 mcg 0.00 Vitamin B6 0.00 60.00 mcg
0.30 mcg 0.05 Vitamin B12 -0.05 0.25 mcg
1000.00 mcg -50.00 Niacin 50.00 1050.00 mcg
16.00 mcg 1.00 Folic Acid -1.00 15.00 mcg
500.00 mcg 50.00 Pantothenic Acid -50.00 450.00 mcg
3.00 mg -1.40 Biotin 1.40 4.40 mcg
12.00 mg 3.00 Vitamin C -3.00 9.00 mg
24.00 mg 0.00 Choline 0.00 24.00 mg