FormulaSeek - Enfamil Nutramigen vs Similac Advance


Updated: 12/7/2024


Introduction

Choosing the right infant formula is a critical decision for new parents, as it forms the foundation of a baby's nutrition and health. While breastfeeding is highly recommended, infant formulas can offer essential nutrients when breastfeeding is not feasible. Similac Advance and Enfamil Nutramigen are two widely used formulas, each with unique ingredients designed to meet different dietary needs. In this blog post, we'll explore these two formulas in-depth to help you make an informed choice.

Nutritional Composition

The nutritional composition of infant formulas includes key macro and micronutrients needed for growth and development. Similac Advance is designed to be as close to breast milk as possible, featuring a blend of cow's milk-based proteins, carbohydrates, and fats. Enfamil Nutramigen, on the other hand, is formulated for infants with special dietary requirements, particularly those with allergies or lactose intolerance.

Similac Advance primarily uses whey protein and lactose as its main carbohydrate source. It includes vegetable oils like safflower, soy, and coconut oil for fats. It is enriched with crucial vitamins and minerals for overall development.

Enfamil Nutramigen contains extensively hydrolyzed casein proteins to minimize allergy risks. It uses corn syrup solids as a carbohydrate source and a blend of vegetable oils, including palm olein, soy, coconut, and high oleic sunflower oil.

Key Differences

Factor Similac Advance Enfamil Nutramigen
Protein Source Whey predominant (60:40 ratio) Hydrolyzed casein-based
Carbohydrate Source Lactose Corn syrup solids
Fat Source Safflower, soy, coconut oil Palm olein, soy, coconut, high oleic sunflower oil
Prebiotics and Probiotics Prebiotics present Probiotics (LGG) present
Omega-3 (DHA/ARA) Levels Enhanced DHA and ARA Contains DHA and ARA
Iron and Calcium Content High iron and calcium High iron and calcium
Estimated Cost per Ounce Approximately $0.89/oz (estimated) Approximately $1.25/oz (estimated)
Organic or Non-GMO Non-GMO Not specified

Special Features and Benefits

Similac Advance is enriched with a unique blend of nutrients designed to support infant brain and eye development, making it ideal for providing complete nutrition during the first year. It includes added prebiotics to promote healthy gut flora.

Enfamil Nutramigen is specifically designed for babies with cow's milk protein allergy or lactose intolerance. Its extensively hydrolyzed proteins are easier to digest and reduce allergic reactions. It also includes probiotics to support digestive health.

Target Audience

Similac Advance is suitable for healthy infants without specific dietary restrictions, designed to support general growth and development from birth.

Enfamil Nutramigen is tailored for infants with an increased risk or existing diagnosis of allergy to cow's milk protein or those suffering from colic linked to food sensitivity. It's also beneficial for lactose-intolerant babies.

Alternatives

Alternatives to Similac Advance

  • Enfamil NeuroPro Infant Formula
  • Gerber Good Start Gentle
  • Earth's Best Organic Infant Formula
  • Happy Baby Organic Infant Formula
  • Kirkland Signature ProCare Non-GMO Infant Formula

Alternatives to Enfamil Nutramigen

  • Similac Alimentum
  • Gerber Extensive HA
  • Elecare Infant Formula
  • Neocate Infant DHA/ARA
  • Hipp HA Combiotic Hypoallergenic

Potential Drawbacks

Similac Advance: While generally well-received, Similac Advance can be more expensive compared to some standard formulas. It might not be suitable for babies with lactose intolerance or cow's milk protein allergy.

Enfamil Nutramigen: The hydrolyzed formula is pricier than standard formulas, and some babies might not enjoy the taste. Availability can be an issue in some areas, and the use of corn syrup solids might be a concern for some parents.

Conclusion

Choosing between Similac Advance and Enfamil Nutramigen largely depends on your baby's specific dietary needs. If your baby is generally healthy with no allergies, Similac Advance provides a complete nutritional package with added prebiotics for gut health. However, if your baby has lactose intolerance or a cow's milk protein allergy, Enfamil Nutramigen's specialized formula with hydrolyzed proteins and probiotics makes it an ideal choice. Always consult with a pediatrician to ensure whichever formula you choose is suitable for your baby's health requirements.

Sources*

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Nutrient comparison

Enfamil Nutramigen +/- Data +/- Similac Advance
5.30 g Fat 0.30 5.60 g
10.30 g Carbohydrate 0.40 10.70 g
2.80 g 0.73 Protein 2.07 g
780.00 mg Linoleic Acid 220.00 1000.00 mg

Minerals comparison

Items in the left column are unique to that formula, same for the right. Items in the middle are in both.

Enfamil Nutramigen +/- Minerals +/- Similac Advance
94.00 mg 49.00 Calcium -49.00 45.00 mg
52.00 mg 10.00 Phosphorus -10.00 42.00 mg
8.00 mg 2.00 Magnesium -2.00 6.00 mg
1.80 mg 0.00 Iron 0.00 1.80 mg
1.00 mg 0.25 Zinc -0.25 0.75 mg
25.00 mcg 20.00 Manganese -20.00 5.00 mcg
75.00 mcg -15.00 Copper 15.00 90.00 mcg
15.00 mcg 0.00 Iodine 0.00 15.00 mcg
2.80 mcg 0.80 Selenium -0.80 2.00 mcg
47.00 mg 23.00 Sodium -23.00 24.00 mg
110.00 mg 5.00 Potassium -5.00 105.00 mg
86.00 mg 21.00 Chloride -21.00 65.00 mg

Vitamins comparison

Vitamins from both formulas are listed in the center. If they exist in a formula they will have a value next to them. The difference will be show under the +/- column for easy visibility.

Enfamil Nutramigen +/- Vitamin +/- Similac Advance
300.00 IU 0.00 Vitamin A 0.00 300.00 IU
60.00 IU 0.00 Vitamin D 0.00 60.00 IU
2.00 IU 0.50 Vitamin E -0.50 1.50 IU
9.00 mcg 1.00 Vitamin K -1.00 8.00 mcg
80.00 mcg -20.00 Thiamin (Vit B1) 20.00 100.00 mcg
90.00 mcg -60.00 Riboflavin (Vit B2) 60.00 150.00 mcg
60.00 mcg 0.00 Vitamin B6 0.00 60.00 mcg
0.30 mcg 0.05 Vitamin B12 -0.05 0.25 mcg
1000.00 mcg -50.00 Niacin 50.00 1050.00 mcg
16.00 mcg 1.00 Folic Acid -1.00 15.00 mcg
500.00 mcg 50.00 Pantothenic Acid -50.00 450.00 mcg
3.00 mg -1.40 Biotin 1.40 4.40 mcg
12.00 mg 3.00 Vitamin C -3.00 9.00 mg
24.00 mg 0.00 Choline 0.00 24.00 mg