FormulaSeek - Enfamil NeuroPro Gentlease RTF vs Similac ProTotal Comfort RTF


Updated: 12/7/2024


Introduction

Choosing the right infant formula is a critical decision for many parents who, for various reasons, are unable to breastfeed. Infant formulas are designed to provide the essential nutrients necessary for a baby’s growth and development, but with numerous options available, the choice can be overwhelming. Similac ProTotal Comfort Ready-to-Feed (RTF) and Enfamil NeuroPro Gentlease RTF are two popular options in the market, each catering to specific dietary and digestive needs. In this blog post, we'll compare these two formulas in detail to help parents make an informed decision.

Nutritional Composition

Understanding the nutritional makeup of an infant formula is vital to ensure it meets your baby's specific needs. Both Similac ProTotal Comfort RTF and Enfamil NeuroPro Gentlease RTF are designed to aid digestion and offer complete nutrition, but they differ in several components.

Similac ProTotal Comfort RTF primarily contains whey protein that is partially hydrolyzed, making it easier to digest for infants with sensitive stomachs. It uses a blend of carbohydrates, including lactose and maltodextrin, and sources its fats from a combination of high oleic safflower oil, soy oil, and coconut oil, with no palm olein oil.

Enfamil NeuroPro Gentlease RTF, on the other hand, uses a partially hydrolyzed nonfat milk and whey protein concentrate, focusing on easy digestion. The carbohydrates are sourced from lactose, corn syrup solids, and maltodextrin, and the fats are derived from palm olein oil, soy oil, and coconut oil.

Key Differences

Feature Similac ProTotal Comfort RTF Enfamil NeuroPro Gentlease RTF
Protein Source Partially hydrolyzed whey protein Partially hydrolyzed nonfat milk and whey protein concentrate
Carbohydrate Source Lactose, maltodextrin Lactose, corn syrup solids, maltodextrin
Fat Source High oleic safflower oil, soy oil, coconut oil Palm olein oil, soy oil, coconut oil
Prebiotics and Probiotics 2'-FL HMO Prebiotics No prebiotics or probiotics listed
Omega-3 (DHA/ARA) Yes Yes
Iron and Calcium Content Balanced for infant needs Balanced for infant needs
Estimated Cost Per Ounce $0.30 - $0.40 $0.25 - $0.35
Organic or Non-GMO Certification Non-GMO Non-GMO

Note: Prices are estimations and may vary depending on location and retailer.

Special Features and Benefits

Similac ProTotal Comfort RTF features a 2'-FL HMO prebiotic, which is structurally identical to one found in breast milk, supporting the infant’s digestive health. Its hydrolyzed protein helps reduce fussiness and gas, which is ideal for babies with sensitive tummies.

Enfamil NeuroPro Gentlease RTF is formulated to ease fussiness, crying, gas, and spit-up within 24 hours. It also includes Omega-3 DHA and an exclusive MFGM (Milk Fat Globule Membrane) that is clinically shown to support cognitive development, similar to nutrients found naturally in breast milk.

Target Audience

Similac ProTotal Comfort RTF is particularly suited for babies experiencing discomfort due to protein sensitivity. It is beneficial for infants with lactose sensitivity, thanks to its partially hydrolyzed whey protein.

Enfamil NeuroPro Gentlease RTF is designed for babies who are fussy, have trouble with gas, or suffer from colic-type symptoms. It offers relief by using a gentle, easy-to-digest protein blend.

Alternative Formulas for Similac ProTotal Comfort RTF

  • Gerber Good Start GentlePro
  • Earth's Best Organic Sensitivity
  • Happy Baby Organic Sensitive
  • Parent's Choice Sensitivity
  • Plum Organics Grow Well Infant Formula

Alternative Formulas for Enfamil NeuroPro Gentlease RTF

  • Enfamil Reguline
  • Similac Sensitive
  • Earth's Best Organic Gentle
  • Gerber Good Start SoothePro
  • Parent's Choice Gentle

Potential Drawbacks

Similac ProTotal Comfort RTF may come with a higher cost per ounce compared to other baby formulas. Additionally, some parents may find the availability problematic depending on their location.

Enfamil NeuroPro Gentlease RTF includes palm olein oil, which some parents prefer to avoid due to potential processing concerns. Cost can also be a significant consideration for families looking for budget-friendly options.

Conclusion

Both Similac ProTotal Comfort RTF and Enfamil NeuroPro Gentlease RTF offer unique benefits geared towards easing digestive discomfort in infants. Choosing between them will depend upon your baby's specific dietary needs and sensitivity profiles. Similac's product is particularly acclaimed for its prebiotics and hydrolyzed protein content, while Enfamil's formula is favored for its maternal-like nutrients that support overall growth and development. As always, it's advised to consult with a pediatrician before transitioning to a new formula to ensure it meets your child’s individual nutritional needs.

Sources*

Buy Enfamil NeuroPro Gentlease RTF Online

Buy Similac ProTotal Comfort RTF Online

+ Links are reviewed periodically for accuracy; failing links might mean the product is currently unavailable.

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Nutrient comparison

Enfamil NeuroPro Gentlease RTF +/- Data +/- Similac ProTotal Comfort RTF
5.30 g Fat 0.10 5.40 g
10.80 g 0.10 Carbohydrate 10.70 g
2.30 g Protein 0.02 2.32 g
780.00 mg Linoleic Acid 220.00 1000.00 mg

Minerals comparison

Items in the left column are unique to that formula, same for the right. Items in the middle are in both.

Enfamil NeuroPro Gentlease RTF +/- Minerals +/- Similac ProTotal Comfort RTF
82.00 mg -23.00 Calcium 23.00 105.00 mg
46.00 mg -29.00 Phosphorus 29.00 75.00 mg
8.00 mg 2.00 Magnesium -2.00 6.00 mg
1.80 mg 0.00 Iron 0.00 1.80 mg
1.00 mg 0.25 Zinc -0.25 0.75 mg
15.00 mcg 10.00 Manganese -10.00 5.00 mcg
75.00 mcg -15.00 Copper 15.00 90.00 mcg
15.00 mcg 0.00 Iodine 0.00 15.00 mcg
2.80 mcg 0.80 Selenium -0.80 2.00 mcg
40.00 mg -4.00 Sodium 4.00 44.00 mg
108.00 mg -10.00 Potassium 10.00 118.00 mg
63.00 mg -2.00 Chloride 2.00 65.00 mg

Vitamins comparison

Vitamins from both formulas are listed in the center. If they exist in a formula they will have a value next to them. The difference will be show under the +/- column for easy visibility.

Enfamil NeuroPro Gentlease RTF +/- Vitamin +/- Similac ProTotal Comfort RTF
300.00 IU 0.00 Vitamin A 0.00 300.00 IU
60.00 IU 0.00 Vitamin D 0.00 60.00 IU
2.00 IU 0.50 Vitamin E -0.50 1.50 IU
9.00 mcg 1.00 Vitamin K -1.00 8.00 mcg
80.00 mcg -20.00 Thiamin (Vit B1) 20.00 100.00 mcg
140.00 mcg -10.00 Riboflavin (Vit B2) 10.00 150.00 mcg
60.00 mcg 0.00 Vitamin B6 0.00 60.00 mcg
0.30 mcg 0.05 Vitamin B12 -0.05 0.25 mcg
1000.00 mcg -50.00 Niacin 50.00 1050.00 mcg
16.00 mcg 1.00 Folic Acid -1.00 15.00 mcg
500.00 mcg 50.00 Pantothenic Acid -50.00 450.00 mcg
3.00 mcg -1.40 Biotin 1.40 4.40 mcg
12.00 mg 3.00 Vitamin C -3.00 9.00 mg
24.00 mg 0.00 Choline 0.00 24.00 mg
24.00 mg 0.00 Inositol 0.00 24.00 mg