FormulaSeek - Enfamil NeuroPro Gentlease RTF vs Enfamil Enspire


Updated: 12/7/2024


Introduction

Choosing the right infant formula is one of the most important decisions a parent can make in supporting their baby’s early development and health. With so many options available, understanding the differences between formulas is crucial. In this blog post, we will compare two prominent formulas: Enfamil NeuroPro Gentlease RTF and Enfamil Enspire. Both are from the trusted Enfamil brand, known for its scientific approach to infant nutrition.

Nutritional Composition

Enfamil NeuroPro Gentlease RTF and Enfamil Enspire have distinct nutritional profiles tailored to meet specific needs. These differences in formulation impact digestion, sensitivity, and overall nutrient uptake by infants.

Enfamil NeuroPro Gentlease RTF: This formula is designed to ease gas, fussiness, and crying, with easy-to-digest proteins. The primary protein source is partially hydrolyzed nonfat milk and whey protein concentrate. It also contains a blend of fats including palm olein, coconut, soy, and high-oleic sunflower oils. Carbohydrates are primarily derived from corn syrup solids.

Enfamil Enspire: Known as a premium formula, Enspire contains ingredients found in breast milk, including lactose as its primary carbohydrate source. This formula uses nonfat milk and whey protein-lipid concentrate as its protein sources. The fat sources are similar, consisting of a blend of palm olein, coconut, soy, and high-oleic sunflower oils.

Key Differences

Feature Enfamil NeuroPro Gentlease RTF Enfamil Enspire
Protein Source Partially Hydrolyzed Nonfat Milk, Whey Protein Concentrate Nonfat Milk, Whey Protein-Lipid Concentrate
Carbohydrate Source Corn Syrup Solids Lactose
Fat Source Palm Olein, Coconut, Soy, High-Oleic Sunflower Oils Palm Olein, Coconut, Soy, High-Oleic Sunflower Oils
Prebiotics and Probiotics None Lactoferrin
Omega-3 (DHA/ARA) Levels Included Included
Iron and Calcium Content Consistent with daily infant needs High, matches typical breast milk ranges
Estimated Cost per Ounce Approx. $0.20 (Prices may vary) Approx. $0.33 (Prices may vary)
Organic or Non-GMO Non-GMO Non-GMO

Special Features and Benefits

Enfamil NeuroPro Gentlease RTF: This formula’s key feature is its partially hydrolyzed proteins, designed to ease digestion and reduce fussiness in sensitive stomachs. It's ready-to-feed for convenience, eliminating the need for mixing with water.

Enfamil Enspire: Enspire boasts MFGM (Milk Fat Globule Membrane) and lactoferrin, nutrients known for promoting cognitive development and immune health, closely mimicking the complete nutrition of breast milk.

Target Audience

Enfamil NeuroPro Gentlease RTF: Ideal for infants who exhibit signs of gas, fussiness, and colic, which may be linked to traditional formulas with whole proteins.

Enfamil Enspire: Best suited for parents seeking a formula that closely replicates the nutritional profile of breast milk, perfect for infants without special dietary needs.

Alternatives

Alternatives to Enfamil NeuroPro Gentlease RTF

  • Similac Pro-Sensitive
  • Gerber Good Start SoothePro
  • Earth's Best Sensitivity
  • Parent’s Choice Sensitivity Formula
  • Happy Baby Organic Sensitive

Alternatives to Enfamil Enspire

  • Similac Pro-Advance
  • Gerber Good Start Gentle
  • Earth’s Best Organic Formula
  • Happy Baby Organics
  • Kirkland Signature ProCare

Potential Drawbacks

Enfamil NeuroPro Gentlease RTF: The cost can be higher due to its ready-to-feed convenience and specialized protein blend. Additionally, its use of corn syrup solids as a carbohydrate source may concern some parents.

Enfamil Enspire: Enspire is one of the more expensive formulas due to its advanced composition, which might not fit every budget. Its reliance on nonfat milk and whey protein may not be ideal for infants with milk protein allergies.

Conclusion

Choosing between Enfamil NeuroPro Gentlease RTF and Enfamil Enspire depends largely on your infant’s specific needs and dietary tolerances. NeuroPro Gentlease offers benefits for babies with digestion and sensitivity issues, while Enspire provides a nutrient-rich, breast-milk-like option suitable for most infants. However, it's crucial that parents consult with a pediatrician before making any changes to their baby's diet, ensuring the chosen formula aligns with their child's unique health needs.

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Nutrient comparison

Enfamil NeuroPro Gentlease RTF +/- Data +/- Enfamil Enspire
5.30 g Fat 5.30 g
10.80 g Carbohydrate 0.30 11.10 g
2.30 g 0.20 Protein 2.10 g
780.00 mg Linoleic Acid 780.00 mg

Minerals comparison

Items in the left column are unique to that formula, same for the right. Items in the middle are in both.

Enfamil NeuroPro Gentlease RTF +/- Minerals +/- Enfamil Enspire
82.00 mg 4.00 Calcium -4.00 78.00 mg
46.00 mg 3.00 Phosphorus -3.00 43.00 mg
8.00 mg 0.00 Magnesium 0.00 8.00 mg
1.80 mg 0.00 Iron 0.00 1.80 mg
1.00 mg 0.00 Zinc 0.00 1.00 mg
15.00 mcg 0.00 Manganese 0.00 15.00 mcg
75.00 mcg 0.00 Copper 0.00 75.00 mcg
15.00 mcg 0.00 Iodine 0.00 15.00 mcg
2.80 mcg 0.00 Selenium 0.00 2.80 mcg
40.00 mg 13.00 Sodium -13.00 27.00 mg
108.00 mg 0.00 Potassium 0.00 108.00 mg
63.00 mg 0.00 Chloride 0.00 63.00 mg

Vitamins comparison

Vitamins from both formulas are listed in the center. If they exist in a formula they will have a value next to them. The difference will be show under the +/- column for easy visibility.

Enfamil NeuroPro Gentlease RTF +/- Vitamin +/- Enfamil Enspire
300.00 IU 0.00 Vitamin A 0.00 300.00 IU
60.00 IU -10.00 Vitamin D 10.00 70.00 IU
2.00 IU 0.00 Vitamin E 0.00 2.00 IU
9.00 mcg 0.00 Vitamin K 0.00 9.00 mcg
80.00 mcg 0.00 Thiamin (Vit B1) 0.00 80.00 mcg
140.00 mcg 0.00 Riboflavin (Vit B2) 0.00 140.00 mcg
60.00 mcg 0.00 Vitamin B6 0.00 60.00 mcg
0.30 mcg 0.00 Vitamin B12 0.00 0.30 mcg
1000.00 mcg 0.00 Niacin 0.00 1000.00 mcg
16.00 mcg 0.00 Folic Acid 0.00 16.00 mcg
500.00 mcg 0.00 Pantothenic Acid 0.00 500.00 mcg
3.00 mcg 0.00 Biotin 0.00 3.00 mcg
12.00 mg 0.00 Vitamin C 0.00 12.00 mg
24.00 mg 0.00 Choline 0.00 24.00 mg
24.00 mg 0.00 Inositol 0.00 24.00 mg