FormulaSeek - Enfamil Enspire vs Similac ProTotal Comfort RTF
Updated: 12/7/2024
Introduction
Choosing the right infant formula is crucial for your baby’s growth and overall health. With myriad options available on the market, it can be overwhelming for parents to make an informed choice. Two popular infant formulas often considered are Similac ProTotal Comfort Ready-To-Feed (RTF) and Enfamil Enspire. Each of these has distinct features suitable for different nutritional needs and conditions. This blog aims to compare these two formulas in detail to aid in making an informed decision.
Nutritional Composition
Understanding the nutritional composition is vital as it directly affects your infant's health. Similac ProTotal Comfort RTF is designed for easier digestion, featuring a protein that is partially hydrolyzed, making it simpler for sensitive tummies. Enfamil Enspire, on the other hand, aims to be as close to breast milk as possible, thanks to its incorporation of lactoferrin and other immune-supporting components.
Key Differences
| Component | Similac ProTotal Comfort RTF | Enfamil Enspire |
|---|---|---|
| Protein Source | Partially Hydrolyzed Whey Protein | Whey-to-Casein Ratio 60:40 |
| Carbohydrate Source | Lactose & Maltodextrin | Lactose |
| Fat Source | Palm Olein, Soy Oil, Coconut Oil | Safflower Oil, Soy Oil |
| Prebiotics and Probiotics | 2'-FL HMO Prebiotic | Lactoferrin & Probiotics |
| Omega-3 (DHA/ARA) Levels | Yes | Yes |
| Iron and Calcium Content | High Iron, Balanced Calcium | Moderate Iron, Balanced Calcium |
| Estimated Cost per Ounce | Approximately $0.50 | Approximately $0.60 |
| Organic or Non-GMO | Non-GMO | Non-GMO |
Note: Prices are estimated and may vary based on location and retailer.
Special Features and Benefits
Similac ProTotal Comfort RTF is formulated with partially hydrolyzed protein, making it ideal for infants with sensitive stomachs. It also contains 2'-FL HMO prebiotic for digestive health. Enfamil Enspire includes a unique blend of lactoferrin, known to support the immune system, and probiotics to aid in gut health and digestion. Additionally, it features the MFGM component, which supports brain development.
Target Audience
Similac ProTotal Comfort RTF is particularly beneficial for babies who have difficulty digesting regular formula and those experiencing gassiness. Enfamil Enspire is well-suited for infants needing immune support and cognitive development, especially those who can digest traditional lactose-based formulas comfortably.
Alternatives to Similac ProTotal Comfort RTF
- Gerber Good Start Gentle
- Enfamil Gentlease
- Earth's Best Organic Sensitivity
- Parent's Choice Tender
- Happy Baby Organic Sensitive
Alternatives to Enfamil Enspire
- Similac Pro-Advance
- Gerber Good Start SoothePro
- Earth's Best Organic Dairy
- Happy Baby Organic
- Plum Organics Grow Well Infant Formula
Potential Drawbacks
Similac ProTotal Comfort RTF might be cost-prohibitive for some families, and its availability can also be inconsistent. It also contains palm olein oil which some parents prefer to avoid. Enfamil Enspire, while offering numerous benefits, is relatively expensive and may not be suitable for all infants, particularly those with lactose sensitivity.
Conclusion
Both Similac ProTotal Comfort RTF and Enfamil Enspire offer unique features tailored to specific infant needs. While Similac is beneficial for sensitive digestive systems, Enfamil Enspire stands out for its immune-supporting components. Ultimately, the best choice aligns with your infant’s specific nutritional needs and family's budget. Always consult with a pediatrician to ensure the selected formula supports your baby’s health and developmental milestones effectively.
Sources*
Buy Enfamil Enspire Online
Buy Similac ProTotal Comfort RTF Online
+ Links are reviewed periodically for accuracy; failing links might mean the product is currently unavailable.
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Nutrient comparison
| Enfamil Enspire | +/- | Data | +/- | Similac ProTotal Comfort RTF |
|---|---|---|---|---|
| 5.30 g | Fat | 0.10 | 5.40 g | |
| 11.10 g | 0.40 | Carbohydrate | 10.70 g | |
| 2.10 g | Protein | 0.22 | 2.32 g | |
| 780.00 mg | Linoleic Acid | 220.00 | 1000.00 mg |
Ingredient comparison
Items in the left column are unique to that formula, same for the right. Items in the middle are in both.
Minerals comparison
Items in the left column are unique to that formula, same for the right. Items in the middle are in both.
| Enfamil Enspire | +/- | Minerals | +/- | Similac ProTotal Comfort RTF |
|---|---|---|---|---|
| 78.00 mg | -27.00 | Calcium | 27.00 | 105.00 mg |
| 43.00 mg | -32.00 | Phosphorus | 32.00 | 75.00 mg |
| 8.00 mg | 2.00 | Magnesium | -2.00 | 6.00 mg |
| 1.80 mg | 0.00 | Iron | 0.00 | 1.80 mg |
| 1.00 mg | 0.25 | Zinc | -0.25 | 0.75 mg |
| 15.00 mcg | 10.00 | Manganese | -10.00 | 5.00 mcg |
| 75.00 mcg | -15.00 | Copper | 15.00 | 90.00 mcg |
| 15.00 mcg | 0.00 | Iodine | 0.00 | 15.00 mcg |
| 2.80 mcg | 0.80 | Selenium | -0.80 | 2.00 mcg |
| 27.00 mg | -17.00 | Sodium | 17.00 | 44.00 mg |
| 108.00 mg | -10.00 | Potassium | 10.00 | 118.00 mg |
| 63.00 mg | -2.00 | Chloride | 2.00 | 65.00 mg |
Vitamins comparison
Vitamins from both formulas are listed in the center. If they exist in a formula they will have a value next to them. The difference will be show under the +/- column for easy visibility.
| Enfamil Enspire | +/- | Vitamin | +/- | Similac ProTotal Comfort RTF |
|---|---|---|---|---|
| 300.00 IU | 0.00 | Vitamin A | 0.00 | 300.00 IU |
| 70.00 IU | 10.00 | Vitamin D | -10.00 | 60.00 IU |
| 2.00 IU | 0.50 | Vitamin E | -0.50 | 1.50 IU |
| 9.00 mcg | 1.00 | Vitamin K | -1.00 | 8.00 mcg |
| 80.00 mcg | -20.00 | Thiamin (Vit B1) | 20.00 | 100.00 mcg |
| 140.00 mcg | -10.00 | Riboflavin (Vit B2) | 10.00 | 150.00 mcg |
| 60.00 mcg | 0.00 | Vitamin B6 | 0.00 | 60.00 mcg |
| 0.30 mcg | 0.05 | Vitamin B12 | -0.05 | 0.25 mcg |
| 1000.00 mcg | -50.00 | Niacin | 50.00 | 1050.00 mcg |
| 16.00 mcg | 1.00 | Folic Acid | -1.00 | 15.00 mcg |
| 500.00 mcg | 50.00 | Pantothenic Acid | -50.00 | 450.00 mcg |
| 3.00 mcg | -1.40 | Biotin | 1.40 | 4.40 mcg |
| 12.00 mg | 3.00 | Vitamin C | -3.00 | 9.00 mg |
| 24.00 mg | 0.00 | Choline | 0.00 | 24.00 mg |
| 24.00 mg | 0.00 | Inositol | 0.00 | 24.00 mg |