FormulaSeek - Enfamil Enspire vs Similac 360 Total Care Sensitive RTF


Updated: 12/7/2024


Introduction

Choosing the right infant formula is crucial for ensuring your baby’s optimal health, growth, and development. Infant formulas are crafted to mimic human breast milk as closely as possible, and while breastfeeding remains the gold standard, many parents rely on formula due to various personal or medical reasons. Among the array of formulas available in the market, Similac 360 Total Care Sensitive RTF and Enfamil Enspire are two popular choices that serve different needs. This blog post will provide a comprehensive comparison of these two formulas to help you make an informed decision.

Nutritional Composition

Nutritional composition is the backbone of any infant formula, as it determines the formula's ability to deliver necessary nutrients for your baby’s development. Similac 360 Total Care Sensitive RTF is designed for babies with sensitive tummies and includes ingredients that are easier to digest. It features a whey-to-casein ratio similar to breast milk and employs partially hydrolyzed protein. In contrast, Enfamil Enspire is known for its emphasis on brain development, containing MFGM (Milk Fat Globule Membrane) and Lactoferrin—substances naturally found in breast milk, touted for their cognitive and immune benefits.

Key Differences

Feature Similac 360 Total Care Sensitive RTF Enfamil Enspire
Protein Source Partially hydrolyzed whey protein Non-hydrolyzed milk protein (casein and whey)
Carbohydrate Source Lactose, Corn Maltodextrin Lactose
Fat Source Safflower Oil, Soy Oil Palm Olein Oil, Coconut Oil
Prebiotics/Probiotics 2’-FL HMO Prebiotic Lactoferrin, MFGM
Omega-3 Levels Available (DHA) Enhanced (DHA/ARA)
Iron Content 1.8 mg/100 kcal 1.8 mg/100 kcal
Calcium Content 83 mg/100 kcal 78 mg/100 kcal
Estimated Cost Per Ounce $0.19* $0.20*
Organic/Non-GMO Certification Non-GMO Non-GMO

*Prices are estimated and may vary based on location and vendor.

Special Features and Benefits

Similac 360 Total Care Sensitive RTF is specially formulated for infants with lactose sensitivity and digestive issues. Its easy-to-digest formula helps reduce fussiness and gas due to lactose intolerance. The inclusion of HMO prebiotics supports a healthy digestive system.
Enfamil Enspire is notable for its focus on brain development and immune support, thanks to its unique ingredients like MFGM and Lactoferrin. Both components are known for contributing to cognitive development and strengthening the immune system, respectively.

Target Audience

Similac 360 Total Care Sensitive RTF is ideal for babies who have lactose sensitivity or experience colic-like symptoms due to lactose intolerance. Conversely, Enfamil Enspire is more suitable for parents who prioritize brain development and immune support in their little ones due to its unique Lactoferrin and MFGM components.

Alternatives to Similac 360 Total Care Sensitive RTF

  • Gerber Good Start GentlePro
  • Enfamil NeuroPro Gentlease
  • Earth’s Best Organic Sensitivity
  • Happy Baby Organic Sensitive
  • Parent’s Choice Tender

Alternatives to Enfamil Enspire

  • Gerber Good Start SoothePro
  • Similac Pro-Advance
  • Happy Baby Organic Infant Formula
  • Earth’s Best Organic Dairy Infant Formula with Iron
  • Parent’s Choice Advantage

Potential Drawbacks

Both formulas, while excellent, come with certain limitations. Similac 360 Total Care Sensitive RTF may be considered expensive by some and might lack certain advanced nutrients prevalent in other formulations. Availability can sometimes be an issue depending on location.
Enfamil Enspire, despite its robust nutrient profile, is also priced on the higher side and may not be suitable for families on a strict budget. Additionally, the presence of palm olein oil is controversial due to potential impacts on bone strength.

Conclusion

Both Similac 360 Total Care Sensitive RTF and Enfamil Enspire offer excellent options catered to different infant needs. Similac is best for those dealing with lactose sensitivity, while Enfamil prioritizes cognitive development and immune support. Ultimately, choosing the right formula will depend on your baby’s specific requirements and conditions. Parents should always consult their pediatrician to make the best-informed decision for their baby’s nutritional needs.

Sources*

Buy Enfamil Enspire Online

Buy Similac 360 Total Care Sensitive RTF Online

+ Links are reviewed periodically for accuracy; failing links might mean the product is currently unavailable.

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Nutrient comparison

Enfamil Enspire +/- Data +/- Similac 360 Total Care Sensitive RTF
5.30 g Fat 0.10 5.40 g
11.10 g 0.20 Carbohydrate 10.90 g
2.10 g Protein 2.10 g
780.00 mg Linoleic Acid 220.00 1000.00 mg

Minerals comparison

Items in the left column are unique to that formula, same for the right. Items in the middle are in both.

Enfamil Enspire +/- Minerals +/- Similac 360 Total Care Sensitive RTF
78.00 mg -6.00 Calcium 6.00 84.00 mg
43.00 mg -13.00 Phosphorus 13.00 56.00 mg
8.00 mg 2.00 Magnesium -2.00 6.00 mg
1.80 mg 0.00 Iron 0.00 1.80 mg
1.00 mg 0.25 Zinc -0.25 0.75 mg
15.00 mcg 10.00 Manganese -10.00 5.00 mcg
75.00 mcg -15.00 Copper 15.00 90.00 mcg
15.00 mcg 0.00 Iodine 0.00 15.00 mcg
2.80 mcg 0.80 Selenium -0.80 2.00 mcg
27.00 mg -3.00 Sodium 3.00 30.00 mg
108.00 mg 1.00 Potassium -1.00 107.00 mg
63.00 mg -2.00 Chloride 2.00 65.00 mg

Vitamins comparison

Vitamins from both formulas are listed in the center. If they exist in a formula they will have a value next to them. The difference will be show under the +/- column for easy visibility.

Enfamil Enspire +/- Vitamin +/- Similac 360 Total Care Sensitive RTF
300.00 IU 0.00 Vitamin A 0.00 300.00 IU
70.00 IU 10.00 Vitamin D -10.00 60.00 IU
2.00 IU 0.50 Vitamin E -0.50 1.50 IU
9.00 mcg 1.00 Vitamin K -1.00 8.00 mcg
80.00 mcg -20.00 Thiamin (Vit B1) 20.00 100.00 mcg
140.00 mcg -10.00 Riboflavin (Vit B2) 10.00 150.00 mcg
60.00 mcg 0.00 Vitamin B6 0.00 60.00 mcg
0.30 mcg 0.05 Vitamin B12 -0.05 0.25 mcg
1000.00 mcg -50.00 Niacin 50.00 1050.00 mcg
16.00 mcg 1.00 Folic Acid -1.00 15.00 mcg
500.00 mcg 50.00 Pantothenic Acid -50.00 450.00 mcg
3.00 mcg -1.40 Biotin 1.40 4.40 mcg
12.00 mg 3.00 Vitamin C -3.00 9.00 mg
24.00 mg 0.00 Choline 0.00 24.00 mg
24.00 mg 0.00 Inositol 0.00 24.00 mg